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Fact Sheet N401. May 2015. World Health Organization.
1 Two azoles posaconazole, fluconazole and an echinocandin, micafungin, are the firstline agents for this purpose see Table 2 for cellular mechanisms of firstline agents.
The frequency and outcome of lupus nephritis: results from an international inception cohort study.
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These investigators also evaluated the relationship of clinical response and TPMT concentration in 52 patients who had been treated with a combination of prednisolone and azathioprine for at least 1 year, and the clinical response was considered favorable if there was no recurrence of pemphigus vulgaris in the first year of treatment.
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Chapters 5-9 of the full version of the original guideline document; see the "Availability of Companion Documents" field).
There are still several medical therapy options which include azathioprine or 6-mercaptopurine, methotrexate, adalimumab (Humira), certolizumab (Cimzia), natalizumab (Tysabri).
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Idiopathic retroperitoneal fibrosis carries a good prognosis, with little effect on long-term morbidity or mortality.
Treatment with azathioprine alone at a dose of 2 mg per kilogram per day reversed the cushingoid facies and weight gain that had been associated with prednisolone therapy in 44 percent of our patients (other complications were rare), and most of the patients reported that they felt better (or at least did not feel worse), despite the development of arthralgias after the prednisolone had been withdrawn.
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We disagree with the assertion that more ESRF in the pulse limb correlates with less rapid improvement in inflammation.
Although the participation of numerous centers could also have introduced certain assessment biases, our observed rates of relapse and adverse events are consistent with those previously reported separately for each drug in other studies of ANCA-associated vasculitis ().
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The UC SUCCESS study enrolled 239 moderate-to-severe ulcerative colitis patients who did not respond to 5-ASA or steroid treatment, assigned them to treatment with azathioprine, infliximab, or azathioprine plus infliximab, and observed them for 16 weeks.
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However, acute myelogenous leukemia as well as solid tumors have been reported in patients with rheumatoid arthritis who have received azathioprine tablets.
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The available case analysis method is preferred to an intention-to-treat with imputation analysis (ITT), in order to avoid making assumptions about the participants for whom outcome data were not available, and furthermore assuming that those with missing outcome data have the same event rate as those who continue.
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One or the other of these tests is used to identify individuals at risk of developing severe side effects from thiopurine therapy.
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These biopsies were analyzed using the 1997 Banff classification () and reviewed blindly by a trained pathologist (L.
However, azathioprine is cheaper than other immunosuppressive agents and can be used instead of steroids.
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Some doctors, knowing that their patients are going elsewhere for alternative therapies, are responding by expanding their own repertoire of services.
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Both the acute cholestasis and the chronic nodular regeneration caused by azathioprine improve upon stopping the medication, but instances of progression to hepatic failure despite discontinuation of azathioprine have been reported with both syndromes.
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